Differential Antibody Responses in 6.B Major Histocompatibility (B) Complex Congenic Chickens
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چکیده
منابع مشابه
Antibody Response Against Sheep Red Blood Cells in Lines Congenic for Major Histocompatibility (B) Complex Recombinants
Six congenic lines containing B complex recombinants R1 = B-F/B-L24, B-G23; R2 = B-F/B-L2, BG23; R3 = B-F/B-L2, B-G23; R4 = B-F/B-L2, B-G23; R5 = B-F/B-L21, B-G19; and R6R6 = B-F/B-L21, B-G23 were tested individually for antibody response against SRBC. R2, R3 and R4 arose from independent recombination events but are serologically identical. Each B complex recombinant was crossed to inbred Line...
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Ten inbred B-congenic Leghorn lines were challenged with two isolates of Staphylococcus aureus at 3 days and 6 wk of age. Significant differences in mortality were observed among such lines when challenged at 3 days with either S. aureus Isolate P4L (moderately pathogenic) or S. aureus Isolate 3727 (highly pathogenic). Line 331 (B2/B2 genotype) had lower mortality than either Line 004 (B17/B17,...
متن کاملResistance, susceptibility, and immunity to Eimeria tenella in major histocompatibility (B) complex congenic lines.
The major histocompatibility (B) complex influence on resistance, susceptibility, and immunity to Eimeria tenella was examined in UCD B complex congenic chicken lines. In Experiment 1, 6-wk-old chicks from 12 UCD congenic lines were weighed and assigned to either challenge or control groups. The challenge group received a dose of 10,000 E. tenella oocysts. Response to challenge was evaluated by...
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We have developed a DNA-based method for defining MHC B system genotypes in chickens. Genotyping by this method requires neither prior determination of allele-specific differences in nucleotide sequence nor the preparation of haplotype-specific alloantisera. Allelic differences at chicken B-F (class I) and B-L (class II) loci are detected in PCR single-strand conformation polymorphism (SSCP) as...
متن کاملMajor Histocompatibility Complex, Class I, B
Description The genes of the Human Leukocyte Antigen (HLA) system reside on chromosome 6, and code for cellsurface proteins that play a crucial role in the presentation of endogenic peptides to effector cells of the immune system. The HLA Class I protein molecule is a heterodimer, made up of two chains; a heavy one and a light one (beta 2 microglobulin). The HLA-B gene is one of the three HLA C...
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ژورنال
عنوان ژورنال: Poultry Science
سال: 1996
ISSN: 0032-5791
DOI: 10.3382/ps.0750203